Science

1. Quantifying the global biodiversity of Proterozoic eukaryotes | Science
   The global diversity of Proterozoic eukaryote fossils is poorly quantified despite its fundamental importance to the understanding of macroevolutionary patterns and dynamics on the early Earth. Here we report a new construction of fossil eukaryote ...
2. A cellulose synthase–like protein governs the biosynthesis of Solanum alkaloids | Science
   Decades of research on the infamous antinutritional steroidal glycoalkaloids (SGAs) in Solanaceae plants have provided deep insights into their metabolism and roles. However, engineering SGAs in heterologous hosts has remained a challenge. We discovered ...
3. Boosting neuronal activity-driven mitochondrial DNA transcription improves cognition in aged mice | Science
   Deciphering the complex interplay between neuronal activity and mitochondrial function is pivotal in understanding brain aging, a multifaceted process marked by declines in synaptic function and mitochondrial performance. Here, we identified an age-...
4. Cellular RNA interacts with MAVS to promote antiviral signaling | Science
   Antiviral signaling downstream of RIG-I–like receptors (RLRs) proceeds through a multi-protein complex organized around the adaptor protein mitochondrial antiviral signaling protein (MAVS). Protein complex function can be modulated by RNA molecules that ...
5. News at a glance: Mars rover’s big ascent, Europa’s ice sheet, and House committee chairs
   The latest in science and policy