Science
The very best in news and research across the sciences.
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Surface restructuring and predictive design of heterogeneous catalysts | Science
Heterogeneous catalysts, which often consist of metal nanoparticles loaded on supports such as metal oxides, can undergo several types of restructuring under reaction and catalytic conditions. Advanced characterizations now allow the surface structure of ...
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Platelet factor 4–induced TH1-Treg polarization suppresses antitumor immunity | Science
The tumor microenvironment (TME) contains a number of immune-suppressive cells such as T helper 1–polarized regulatory T cells (TH1-Treg cells). However, little is known about the mechanism behind the abundant presence of TH1-Treg cells in the TME. We ...
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Specific tRNAs promote mRNA decay by recruiting the CCR4-NOT complex to translating ribosomes | Science
The CCR4-NOT complex is a major regulator of eukaryotic messenger RNA (mRNA) stability. Slow decoding during translation promotes association of CCR4-NOT with ribosomes, accelerating mRNA degradation. We applied selective ribosome profiling to further ...
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Chemically induced proximity reveals a Piezo-dependent meiotic checkpoint at the oocyte nuclear envelope | Science
Sexual reproduction relies on robust quality control during meiosis. Assembly of the synaptonemal complex between homologous chromosomes (synapsis) regulates meiotic recombination and is crucial for accurate chromosome segregation in most eukaryotes. ...
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Do ‘blue zones,’ supposed havens of longevity, rest on shaky science?
Critics say extraordinary life spans reflect faulty record keeping, not healthy lifestyles