Proceedings of the National Academy of Sciences: Proceedings of the National Academy of Sciences: Table of Contents

1. In This Issue
   Proceedings of the National Academy of Sciences, Volume 122, Issue 15, April 2025. <br/>
2. Unsupervised learning of structural relaxation in supercooled liquids from short-term fluctuations
   Proceedings of the National Academy of Sciences, Volume 122, Issue 15, April 2025. <br/>SignificanceLinking unperturbed amorphous structures to the dramatic slowdown and heterogeneity in dynamics has been a challenge in glass transition studies. Many supervised machine learning techniques have shown excellent performance in predicting ...
3. Bourbon and Mycbp function with Otu to promote Sxl protein expression in the Drosophila female germline
   Proceedings of the National Academy of Sciences, Volume 122, Issue 15, April 2025. <br/>SignificanceThrough a genetic screen, we identified a gene calledbourbon, the loss of which causes sterility and the formation of cystic tumors. Further experiments reveal that Bbn cooperates with Ovarian Tumor (Otu) and aDrosophilaortholog of the ...
4. FAO-fueled OXPHOS and NRF2-mediated stress resilience in MICs drive lymph node metastasis
   Proceedings of the National Academy of Sciences, Volume 122, Issue 15, April 2025. <br/>SignificanceLymph node (LN) metastasis is a critical step in cancer progression, yet the metabolic adaptations that enable tumor cells to survive and colonize this microenvironment remain unclear. This study identifies a rare subpopulation of metastasis-...
5. Closure of orbits of the pure mapping class group in the character variety
   Proceedings of the National Academy of Sciences, Volume 122, Issue 15, April 2025. <br/>SignificanceThe character variety of a surface is a scheme with a rich but discrete set of automorphisms given by the mapping class group of the surface. The action of this group on the real points of the character variety has been extensively ...